_____ look very tired.

Hint:

Personal pronouns are words which we use in place of nouns to talk about a person, place, animal or thing.
I, first person, singular, is used to refer to ourselves.
We, first person, plural, is used to refer to a group of people or more than one person including us.
You, second person, singular or plural is used as a pronoun while talking to another person or more than one person.