science
Grade-10
Easy

Question

_____________ mutation causes sickle cell anemia.

  1. Frameshift mutation.

  2. Point mutation.

  3. Translocation mutation. 

  4. None of the above.

Hint:

A group of diseases that cause the deformation or destruction of red blood cells. It is caused by genetic changes that instruct the body to make an iron-rich compound called hemoglobin in red blood cells.

The correct answer is:

Point mutation.


    • Point mutations are genetic alterations in which a single nucleotide base is altered, inserted, or deleted in a DNA or RNA sequence.
    • A single-point mutation occurs in sickle cell anemia. This point mutation occurs in the beta-hemoglobin gene. This converts the GAG ​​codon (6th codon) to his GUG codon, which codes for the amino acid valine instead of glutamic acid.

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