science
Grade-11
Easy
Question
Which disease or disorder causes people to have abnormal hemoglobin?
- Turner's syndrome
- Sickle cell anemia
- Cystic fibrosis
- Hemophilia
Hint:
Disease that is caused due to reduced hemoglobin level.
The correct answer is: Sickle cell anemia
Red blood cells posses a protein called hemoglobin which helps in exchange of gases. Reduced level of hemoglobin in blood causes anemia.
Hemoglobin "S" is an abnormal type of hemoglobin causing the change in shape of the red blood cells. This type of hemoglobin alters the RBCs to become rigid and sickle shaped. The resulting RBCs posses lesser surface area with minimal potency of gaseous exchange.
Hemophilia is a blood disorder caused due to deficiency of clotting factor and not hemoglobin.
Cystic fibrosis affects the respiratory system alone and is not associated with hemoglobin or blood.
Turner syndrome is a condition where a female posses only one X chromosome (sex chromosome).
- Disorder or disease associated with hemoglobin causes anemia
- In sickle cell anemia, the individual posses an altered "S" hemoglobin causing the RBCs to alter its shape
- The RBCs with "S" hemoglobin become rigid and sickle shaped with inability to transport gases, resulting in anemia
- Hemophilia is the disorder due to deficiency of clotting factors
- Cystic fibrosis affects respiratory system
- Females possessing single X chromosome are termed with a medical condition called Turner syndrome
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Which disease or disorder is the result of having an extra chromosome?
- Down syndrome is also termed as trisomy 21
- Individuals posses an extra chromosome at 21 position
- Trisomy 21 is caused due to improper separation of chromosomes during meiosis
- Cystic fibrosis is an autosomal recessive disorder
- Color blindness is an autosomal dominant disorder
- Hemophilia is a monogenic genetic disorder
Which disease or disorder is the result of having an extra chromosome?
scienceGrade-11
- Down syndrome is also termed as trisomy 21
- Individuals posses an extra chromosome at 21 position
- Trisomy 21 is caused due to improper separation of chromosomes during meiosis
- Cystic fibrosis is an autosomal recessive disorder
- Color blindness is an autosomal dominant disorder
- Hemophilia is a monogenic genetic disorder
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- The disorder is caused due to alteration in CFRT gene
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- Other disorders mentioned are not autosomal recessive in nature
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- Cystic fibrosis results in breathing disorder of the affected individual due to increased thick mucus secretion
- The disorder is caused due to alteration in CFRT gene
- It is a type of autosomal recessive disorder, having both copies of gene altered in a cell
- Other disorders mentioned are not autosomal recessive in nature
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