science
Grade-10
Easy

Question

5BU is an example of ___________.    

  1. Deaminating agents

  2. Alkylating agents.

  3. Base analogs. 

  4. Hydroxylating agents. 

Hint:

5BU has structure similar to thymine.

The correct answer is:

Base analogs. 


    • 5BromoUracil is a base analog
    • It comprises of a uracil base which is a bromine derivative
    • It has structure same as that of thymine
    • 5BU is capable of replacing thymine in DNA causing mutation
    • The comparative structure of 5BU, thymine and uracil can be found in https://royalsocietypublishing.org/doi/10.1098/rsta.2016.0202

    • Base analogues have structure similar to the common purine and pyrimidine bases

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