science
Grade-10
Easy

Question

Nitrous acid is a __________ agent.

  1. Alkylating agent.

  2. Deaminating agent.

  3. Hydroxylating agent.

  4. None of the above

hintHint:

Nitrous acid converts cytosine to uracil and ammonia.

The correct answer is:

Deaminating agent.


    • Nitrous acid is a deaminating agent
    • The deamination is the process of removal of an amino group 
    • In DNA, the deaminating agent causes removal of nitrogen containing groups (in bases) 
    • Deamination of bases causes conversion of one base to another base. Example: Cytosine (pyrimidine) is converted to uracil (purine) and ammonia
    • The substitution of a pyrimidine to a purine causes change in the base pairing during subsequent replication and transcription process

    Nitrous acid also converts adenine to hypoxanthine and guanine to xanthine

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