science
Grade-10
Easy

Question

Examples of base analogs are ________.

  1. Ethidium bromide.

  2. Acridine dyes.

  3. Mustard gas.

  4. 5-Bromouracil.

hintHint:

Compound which is a derivative of pyrimidine.

The correct answer is:

5-Bromouracil.


    • Base analogues are molecules with structure similar to that of the purine or pyrimidine bases
    • The base analogues can substitute the place of a base and cause mutation
    • 5BromoUracil and 2AminoPurine are common base analogues
    • The substitution of a base analogue can cause change in base pairing during replication
    • In some cases, this results in synthesis of unwanted amino acid during transcription 

    • Base analogues are naturally occurring molecules having similar structure to common bases
    • 5BU has structure similar to thymine
    • 2aminopurine has structure similar to purine

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